Explore Mayersville, MS

Mayersville, Mississippi is a small town located in Issaquena County. With a population of just over 500 residents, Mayersville is known for its tight-knit community and rural charm. The town is situated along the Mississippi River, offering picturesque views and a peaceful atmosphere. Despite its small size, Mayersville has a rich history, being one of the oldest settlements in the county. Visitors can explore historic landmarks, such as the Mayersville Courthouse, and enjoy outdoor activities like fishing and boating on the river.


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